The Various Functions of B1211
Vit B12 is essential in the production of red blood cells and therefore how oxygen is carried throughout the body. In addition to helping get oxygen to the cells, vitamin B12 also supports energy production since it’s a cofactor for enzymes involved in the Kreb’s cycle which leads to the production of adenosine triphosphate (ATP), the energy currency of the cell
Brain and Central Nervous System
Vit B12 is also essential for the development, myelination, and function of the central nervous system, helping form the myelin sheath around neurons. Acting as a critical brain nutrient, it’s involved in the synthesis of neurotransmitters that send signals to the rest of the body for many important functions.
Alongside folate, vitamin b12 regulates homocysteine metabolism which is a protein that has been linked to mood and cardiovascular issues if elevated in the blood. Due to its role in methylation, it’s essential for many functions in the body including gene expression, DNA repair & maintenance, and nervous system health.
Vitamin B12 Deficiency
Vit B12 deficiency is believed to be one of the most common nutrient deficiencies in the world. Populations that are most at risk include the elderly, vegetarians/vegans, those with gastrointestinal disorders or who’ve had intestinal surgeries, individuals with pernicious anemia, and those taking antibiotic and/or stomach acid-lowering medications frequently.5-10 Prolonged vitamin B-12 deficiency can lead to fatigue, anemia, dysbiosis, muscle weakness, nerve damage, and mood disturbances.
People who have a high risk for deficiency include:11
- Chronic fatigue & weakness
- Muscle aches, joint pain, and trouble exercising
- Poor memory and/or ability to focus
- Mood changes include increased depression and anxiety & nervousness
- Dizziness and/or shortness of breath
- Poor appetite and/or digestive problems like constipation, nausea, diarrhea or cramping
Aceva's Active B12 Difference:
Aceva’s Active B Liquid features a unique ratio of the two biologically active forms of vit B12 called methylcobalamin and adenosylcobalamin in a highly absorbable sublingual form. The majority of other vit b12 products contain cyanocobalamin form which requires the body to convert it to one of the active forms in the liver. Cyanocobalamin also contains a cyanide molecule and can potentially be toxic to the body. Other products may only contain methylcobalamin which is beneficial but does not provide the adenosylcobalamin form which is the “mitochondrial ready” form. The active forms of B12 have been shown to bypass several steps in the absorption cycle which is a benefit for those with compromised digestion. Methyl B12 & adenosyl B12 absorb, retain and increase tissue concentration much better than the cyanocobalamin form of vit B12.12 Their combined use offers a myriad of benefits that would not be able to be achieved alone.
Methylcobalamin contains a methyl group beneficial for methylation reactions including those needed for DNA repair and maintenance, homocysteine metabolism, neurotransmitter production, fetal development and nervous system health. It’s been shown to bypass several potential issues in the intestinal absorption cycle which means it has higher bioavailability.13
Adenosylcobalamin is the mitochondrial form of vit B12 and is the primary storage form our bodies tuck away in the liver for times of need. Research has shown this form of vit B12 along with carnitine promoted cerebral mass growth, neuronal volume and neocortical layer thickness in the brain and fully restored normal structure of the neocortex in the brain and has been shown to eliminate work rate inconsistencies and improve mental productivity. 14-15
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.