5-HTP

Enhances Serotonin Levels
Mood Support, Sleep Aid & Appetite Control 

A powerful amino acid metabolite that your body converts into serotonin naturally, 5-HTP (or 5-hydroxytryptophan) helps you stabilize your mood, control your appetite, and even get a better night’s sleep. Serotonin – a chemical messenger for your brain – has also been shown to help promote feelings of well-being and happiness. Take 1 or more capsule daily or as recommended by your healthcare professional.

  • 5-HTP For A Better Mood And Improved Sleep

    Mood disorders, including depression, are associated with serotonin imbalances in the brain. 5-HTP crosses the blood-brain barrier and is decarboxylated to serotonin with the help of vitamin B6 and has been shown to be effective in depressive disorders. Supplementing 5-HTP for those suffering with insomnia has been shown to increase R.E.M sleep from 5 to 53%.1 In addition to its impact on mood disorders and insomnia, 5-HTP has a significant impact on many other conditions including fibromyalgia, migraine headaches and obesity.*

    Additional Impact 5-HTP Can Make On Your Health

    Fibromyalgia

    Low serotonin is common in those with fibromyalgia. Double-blind research trials have reported that supplementing with 100mg of 5-HTP three times per day relieves some symptoms of fibromyalgia.2-3 Insomnia - 200 mg 2 hrs. before bedtime/400 mg at bedtime A single 100-mg nighttime dose of 5-HTP was sufficient to improve the duration and depth of sleep in one placebo-controlled trial.4 In a double-blind trial of people without insomnia, supplementation with 5-HTP (200 mg at 9:15 p.m. and 400 mg at 11:15 p.m.) increased rapid-eye-movement (REM) sleep, presumably indicating improved sleep quality.5

    Migraine Headache

    Forty people with migraine headaches received either 200mg of 5-HTP per day or methysergide (a migraine medication) for forty days. Both compounds reduced the frequency of migraines by 50%.6 Migraine attacks were reduced in frequency, severity, and duration in 90% of those taking 400 mg per day of 5-HTP in a double-blind placebo-controlled trial.7

    Obesity

    In a 12-week double-blind trial, overweight females took 600 to 900 mg of 5-HTP and lost significantly more weight than those women who received the placebo.8 In another double-blind trial obese people with type 2 diabetes took 750 mg of 5-HTP for two weeks with no dietary restrictions (some reduced their carbohydrate and fat intake voluntarily). The group taking the 5-HTP lost 23 times more weight compared to the placebo group (4.6 pounds vs 0.2 pounds respectively).9

    Citations

    1. Wyatt, R. J., et al. "Effects of 5-hydroxytryptophan on the sleep of normal human subjects." Electroencephalography and clinical neurophysiology 30.6 (1971): 505-509.
    2. Puttini PS, Caruso I. Primary fibromyalgia syndrome and 5-hydroxy-L-tryptophan: a 90-day open study. J Int Med Res 1992;20:182-9.
    3. Moldofsky H, Warsh JJ. Plasma tryptophan and musculoskeletal pain in non-articular rheumatism (“fibrositis syndrome”). Pain 1978;5:65-71.
    4. Soulairac A, Lambinet H. Etudes cliniques de líaction du precurseur de la serotonine le L-5-hydroxy-tryptophane, sur les troubles du sommeil.
    5. Schweiz Bundschau Med (PRAXIS) 1998;77(34a):19-23 [in French].
    6. Wyatt RJ, Zarcone V, Engelman K, et al. Effects of 5-hydroxytryptophan on the sleep of normal human subjects. Electroencephalogr Clin Neurophysiol1971;30:505-9.
    7. Titus F, Davalos A, Alom J, Codina A. 5-hydroxytryptophan versus methysergide in the prophylaxis of migraine. Eur Neurol 1986;25:327-9.
    8. De Benedittis G, Massei R. 5-HT precursors in migraine prophylaxis: A double-blind cross-over study with L-5-hydroxytryptophan versus placebo. Clin J Pain1986;3:123-9.
    9. Cangiano C, Ceci F, Cascino A, et al. Eating behavior and adherence to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophan. Am J Clin Nutr1992;56:863–7.

    * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

    WARNING:  Consuming this product can expose you to chemicals including lead, which is known to the State of California to cause birth defects or other reproductive harm.  For more information go to www.P65Warnings.ca.gov/food

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