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5-HTP
5-HTP
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$49.71 USD
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5-Hydroxytryptophan
- Peace & Sleep -
A powerful amino acid that your body naturally converts into serotonin - 5-HTP can help you stabilize your mood, control your appetite, and provide higher quality sleep. Serotonin, the 'chemical messenger' in your brain – has also been shown to promote feelings of well-being & happiness.
~ The Bigger Picture ~
Mood disorders, like depression, are associated with serotonin imbalances in the brain. 5-HTP crosses the blood-brain barrier and then decarboxylated to serotonin with the help of vitamin B6 and has been shown to be effective in depressive disorders. Supplementing 5-HTP for those suffering with insomnia has been shown to increase R.E.M sleep from 5% to 53%.
Additional Impacts
Weight-Management
In a 12-week double-blind trial, overweight females took 600 to 900 mg of 5-HTP and lost significantly more weight than those women who received the placebo.8 In another double-blind trial obese people with type 2 diabetes took 750 mg of 5-HTP for two weeks with no dietary restrictions (some reduced their carbohydrate and fat intake voluntarily). The group taking the 5-HTP lost 23 times more weight compared to the placebo group (4.6 pounds vs 0.2 pounds respectively).9
Migraine Headaches
Forty people with migraine headaches received either 200mg of 5-HTP per day or methysergide (a migraine medication) for forty days. Both compounds reduced the frequency of migraines by 50%.6 Migraine attacks were reduced in frequency, severity, and duration in 90% of those taking 400 mg per day of 5-HTP in a double-blind placebo-controlled trial.7
Fibromyalgia
Low serotonin is common in those with fibromyalgia. Double-blind research trials have reported that supplementing with 100mg of 5-HTP three times per day relieves some symptoms of fibromyalgia.2-3 Insomnia - 200 mg 2 hrs. before bedtime/400 mg at bedtime A single 100-mg nighttime dose of 5-HTP was sufficient to improve the duration and depth of sleep in one placebo-controlled trial.4 In a double-blind trial of people without insomnia, supplementation with 5-HTP (200 mg at 9:15 p.m. and 400 mg at 11:15 p.m.) increased rapid-eye-movement (REM) sleep, presumably indicating improved sleep quality.5
Collapsible content
Suggested Use
As a dietary supplement, take one (1) or more capsules per day or as recommended by your health care professional.
Formulated To Be Free of Allergens Derived From:
Wheat, soy, dairy, eggs, fish, crustacean shellfish, tree nuts, peanuts, artificial preservatives, sweeteners, colors and flavors.
Caution: As with any dietary supplement, consult your healthcare professional before using this product, especially if you are pregnant, nursing, anticipate surgery, take any medication or are otherwise under medical supervision.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Citations:
1. Wyatt, R. J., et al. "Effects of 5-hydroxytryptophan on the sleep of normal human subjects." Electroencephalography and clinical neurophysiology 30.6 (1971): 505-509.
2. Puttini PS, Caruso I. Primary fibromyalgia syndrome and 5-hydroxy-L-tryptophan: a 90-day open study. J Int Med Res 1992;20:182-9.
3. Moldofsky H, Warsh JJ. Plasma tryptophan and musculoskeletal pain in non-articular rheumatism (“fibrositis syndrome”). Pain 1978;5:65-71.
4. Soulairac A, Lambinet H. Etudes cliniques de líaction du precurseur de la serotonine le L-5-hydroxy-tryptophane, sur les troubles du sommeil.
5. Schweiz Bundschau Med (PRAXIS) 1998;77(34a):19-23 [in French].
6. Wyatt RJ, Zarcone V, Engelman K, et al. Effects of 5-hydroxytryptophan on the sleep of normal human subjects. Electroencephalogr Clin Neurophysiol1971;30:505-9.
7. Titus F, Davalos A, Alom J, Codina A. 5-hydroxytryptophan versus methysergide in the prophylaxis of migraine. Eur Neurol 1986;25:327-9.
8. De Benedittis G, Massei R. 5-HT precursors in migraine prophylaxis: A double-blind cross-over study with L-5-hydroxytryptophan versus placebo. Clin J Pain1986;3:123-9.
9. Cangiano C, Ceci F, Cascino A, et al. Eating behavior and adherence to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophan. Am J Clin Nutr1992;56:863–7.
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