Enhances Serotonin Levels
Mood Support, Sleep Aid & Appetite Control 

A powerful amino acid metabolite that your body converts into serotonin naturally, 5-HTP (or 5-hydroxytryptophan) helps you stabilize your mood, control your appetite, and even get a better night’s sleep. Serotonin – a chemical messenger for your brain – has also been shown to help promote feelings of well-being and happiness. Take 1 or more capsule daily or as recommended by your healthcare professional.

  • 5-HTP For A Better Mood And Improved Sleep

    Mood disorders, including depression, are associated with serotonin imbalances in the brain. 5-HTP crosses the blood-brain barrier and is decarboxylated to serotonin with the help of vitamin B6 and has been shown to be effective in depressive disorders. Supplementing 5-HTP for those suffering with insomnia has been shown to increase R.E.M sleep from 5 to 53%.1 In addition to its impact on mood disorders and insomnia, 5-HTP has a significant impact on many other conditions including fibromyalgia, migraine headaches and obesity.*

    Additional Impact 5-HTP Can Make On Your Health


    Low serotonin is common in those with fibromyalgia. Double-blind research trials have reported that supplementing with 100mg of 5-HTP three times per day relieves some symptoms of fibromyalgia.2-3 Insomnia - 200 mg 2 hrs. before bedtime/400 mg at bedtime A single 100-mg nighttime dose of 5-HTP was sufficient to improve the duration and depth of sleep in one placebo-controlled trial.4 In a double-blind trial of people without insomnia, supplementation with 5-HTP (200 mg at 9:15 p.m. and 400 mg at 11:15 p.m.) increased rapid-eye-movement (REM) sleep, presumably indicating improved sleep quality.5

    Migraine Headache

    Forty people with migraine headaches received either 200mg of 5-HTP per day or methysergide (a migraine medication) for forty days. Both compounds reduced the frequency of migraines by 50%.6 Migraine attacks were reduced in frequency, severity, and duration in 90% of those taking 400 mg per day of 5-HTP in a double-blind placebo-controlled trial.7


    In a 12-week double-blind trial, overweight females took 600 to 900 mg of 5-HTP and lost significantly more weight than those women who received the placebo.8 In another double-blind trial obese people with type 2 diabetes took 750 mg of 5-HTP for two weeks with no dietary restrictions (some reduced their carbohydrate and fat intake voluntarily). The group taking the 5-HTP lost 23 times more weight compared to the placebo group (4.6 pounds vs 0.2 pounds respectively).9


    1. Wyatt, R. J., et al. "Effects of 5-hydroxytryptophan on the sleep of normal human subjects." Electroencephalography and clinical neurophysiology 30.6 (1971): 505-509.
    2. Puttini PS, Caruso I. Primary fibromyalgia syndrome and 5-hydroxy-L-tryptophan: a 90-day open study. J Int Med Res 1992;20:182-9.
    3. Moldofsky H, Warsh JJ. Plasma tryptophan and musculoskeletal pain in non-articular rheumatism (“fibrositis syndrome”). Pain 1978;5:65-71.
    4. Soulairac A, Lambinet H. Etudes cliniques de líaction du precurseur de la serotonine le L-5-hydroxy-tryptophane, sur les troubles du sommeil.
    5. Schweiz Bundschau Med (PRAXIS) 1998;77(34a):19-23 [in French].
    6. Wyatt RJ, Zarcone V, Engelman K, et al. Effects of 5-hydroxytryptophan on the sleep of normal human subjects. Electroencephalogr Clin Neurophysiol1971;30:505-9.
    7. Titus F, Davalos A, Alom J, Codina A. 5-hydroxytryptophan versus methysergide in the prophylaxis of migraine. Eur Neurol 1986;25:327-9.
    8. De Benedittis G, Massei R. 5-HT precursors in migraine prophylaxis: A double-blind cross-over study with L-5-hydroxytryptophan versus placebo. Clin J Pain1986;3:123-9.
    9. Cangiano C, Ceci F, Cascino A, et al. Eating behavior and adherence to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophan. Am J Clin Nutr1992;56:863–7.

    * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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